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Cayman ?-Mangostin, 1,3,6-Trihydroxy-7-Methoxy-2,8-Bis(3-Methyl-2
Cayman ?-Mangostin, 1,3,6-Trihydroxy-7-Methoxy-2,8-Bis(3-Methyl-2-Buten-1-Yl)-9h-Xanthen-9-One, 25 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$88.00
Your Price
$88.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-29108-25 |
| MFG.PART: | 29108-25 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
(S)-Flurbiprofen is the COX-active enantiomer of the non-selective COX inhibitor flurbiprofen (Item No. ) with IC50 values of 0.48 and 0.47 µM for COX-1 and COX-2, respectively, in guinea pig whole blood. It inhibits the release of 6-keto prostaglandin F1α (6-keto-PGF1α; Item No. ) and thromboxane B2 (TXB2; Item No. ) from rat whole blood, gastric mucosa, lung, and jejunal tissue ex vivo in a dose-dependent manner. (S)-Flurbiprofen (1 nM) inhibits basal and bradykinin-, serotonin-, and histamine-stimulated prostaglandin E2 (PGE2) release from isolated skin flaps of rat lower hind paws. It also inhibits release of the neuroinflammatory marker calcitonin gene-related peptide (CGRP; Item Nos. | | ) when used at a concentration of 1 μM. In vivo, (S)-flurbiprofen reduces the number of flinches per minute in the formalin test in rats, indicating antinociceptive activity.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(S)-
CAS Number
51543-39-6
Molecular Formula
C15H13FO2
Formula Weight
244.3
Purity
≥99%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 25 mg/ml
- PBS (pH 7.2): 0.9 mg/ml
λmax
247 nm
SMILES
FC1=CC([C@@H](C(O)=O)C)=CC=C1C2=CC=CC=C2
InChi Code
InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)
InChi Key
SYTBZMRGLBWNTM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29108-25 |
|---|---|
| Supplier Part Number | 29108-25 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/29108m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |
| CAS Number | 1551491 |