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Cayman Ginkgolide J
![](https://netam2po.netascientific.info/media/skin/seal2.png)
![](https://netam2po.netascientific.info/media/skin/seal.png)
NETA PART: | CAYM-29163-10 |
MFG.PART: | 29163-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Hederagenin is a triterpene saponin that has been found in P. eximia with diverse biological activities.,,,, It increases production of reactive oxygen species (ROS), reduces colony formation, and induces apoptosis in cisplatin-resistant head and neck carcinoma (HNC) cells. In vivo, hederagenin (50, 100, and 200 mg/kg) suppresses tumor growth in a cisplatin-resistant HNC mouse xenograft model. It reduces aortic atherosclerotic lesion area, serum cholesterol and LDL levels, and inducible nitric oxide synthase (iNOS) protein levels in a rat model of atherosclerosis. Hederagenin (50 mg/kg) reduces ethanol-induced production of TNF-α, IL-6, and COX-2, alcohol dehydrogenase 2 (ALDH2) mRNA expression, and liver damage in a rat model of alcohol-induced hepatotoxicity. It also induces autophagy and inhibits oligomerization of α-synuclein in a mouse model of Parkinsons disease induced by MPTP.
WARNING This product is not for human or veterinary use.
Technical Information
- Astrantiagenin E
- Caulosapogenin
- Hederagenic Acid
- NSC 24954
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
Shipping & Storage Information
SKU | CAYM-29163-10 |
---|---|
Supplier Part Number | 29163-10 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/29163m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 107438-79-9 |