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Cayman Cp 471,474; Purity- Greater Than Or Equal To 98%; Size- 10
NETA PART: | CAYM-29442-10 |
MFG.PART: | 29442-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Seselin is an angular pyranocoumarin that has been found in M. semecarpifolia and has diverse biological activities.,,, It is cytotoxic to P388 and HT-29 cells in vitro (EC50s = 8.66 and 9.94 μg/ml). Seselin (0.5, 4.5, and 40.5 mg/kg) reduces acetic acid-induced writhing in mice. It also reduces paw licking in the first and second phases of the formalin test in mice when administered 30 minutes prior to formalin. Seselin (3, 10, and 30 mg/kg) decreases serum levels of IL-1β, IL-6, and TNF-α in a mouse model of sepsis induced by cecal ligation and puncture and increases survival when administered at a dose of 30 mg/kg. It reduces ear edema induced by phorbol 12-myristate 13-acetate (TPA; Item No. ) in mice (ED45 = 0.25 mg/ear).
WARNING This product is not for human or veterinary use.
Technical Information
Shipping & Storage Information
SKU | CAYM-29442-10 |
---|---|
Supplier Part Number | 29442-10 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/29442m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 210755-45-6 |