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Cayman 12-Keto Lithocholic Acid
NETA PART: | CAYM-29547-5 |
MFG.PART: | 29547-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
12-keto Lithocholic acid is a metabolite of the secondary bile acid deoxycholic acid (DCA; Item Nos. | )., Fecal levels of 12-keto lithocholic acid are elevated in rats fed a diet supplemented with cholic acid (Item No. ) or DCA compared with rats fed a control diet or a diet supplemented with cholesterol (Item No. ), hyodeoxycholic acid (HDCA; Item No. ), or lithocholic acid (LCA; Item No. ). 12-keto Lithocholic acid activates the human pregnane X receptor (PXR; EC50 = 31.3 μM in a cell-based transactivation assay). 12-keto Lithocholic acid levels are increased in duodenal bile from patients with type 2 diabetes.
WARNING This product is not for human or veterinary use.
Technical Information
- 12-keto LCA
- 12-keto Lithocholate
- 12-KLCA
- 12-oxo LCA
- 12-oxo Lithocholate
- 12-oxo Lithocholic Acid
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
Shipping & Storage Information
SKU | CAYM-29547-5 |
---|---|
Supplier Part Number | 29547-5 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/29547m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 5130-29-0 |