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Cayman Ky 05009
Cayman Ky 05009 - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$37.00
Your Price
$37.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-29552-1 |
| MFG.PART: | 29552-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
KY 05009 is an inhibitor of TRAF2- and NCK-interacting kinase (TNIK; Ki = 100 nM). It inhibits TGF-β1-induced Wnt, NF-κB, ERK, and JNK signaling and prevents TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in A549 lung cancer cells without inducing cytotoxicity when used at a concentration of 10 μM. KY 05009 inhibits TNF-β1-induced A549 cell migration. It also induces apoptosis in RPMI-8226 multiple myeloma cells in a concentration-dependent manner.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-[(4-
CAS Number
1228280-29-2
Molecular Formula
C18H16N4O2S
Formula Weight
352.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: sonicated
λmax
244, 277, 356 nm
SMILES
NC(C1=C(NC(C2=CC=C(C)C=C2)=O)SC(NC3=CC=CC=C3)=N1)=O
InChi Code
InChI=1S/C18H16N4O2S/c1-11-7-9-12(10-8-11)16(24)22-17-14(15(19)23)21-18(25-17)20-13-5-3-2-4-6-13/h2-10H,1H3,(H2,19,23)(H,20,21)(H,22,24)
InChi Key
WCEDGRTWDSHZHF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29552-1 |
|---|---|
| Supplier Part Number | 29552-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/29552m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1228280-29-2 |