We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman 8-Bromoadenosine 5?-Triphosphate (Sodium Salt Hydrate), 8-
Cayman 8-Bromoadenosine 5?-Triphosphate (Sodium Salt Hydrate), 8-Bromo-Adenosine 5?-(Tetrahydrogen Triphosphate), Sodium Salt Hydrate, 10 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$243.00
Your Price
$243.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-30573-10 |
| MFG.PART: | 30573-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Cannabinoids (CBs) and their synthetic analogs produce biochemical and pharmacological effects by interacting with the central CB1 and peripheral CB2 receptors. The CB2 receptor has emerged as a pharmacotherapeutic target for treating osteoporosis, as well as for eliciting antinociceptive effects in various models of pain. 4-Quinolone-3-carboxamide CB2 ligand is a selective, high-affinity ligand of the CB2 receptor, displaying a Ki value of 0.6 nM (Ki >10,000 nM for CB1) in vitro. At a dose of 6 mg/kg, 4-quinolone-3-carboxamide CB2 ligand exhibits antinociceptive activity in a formalin test of nocifensive response in mice. This analgesic affect is not significantly reversed by the CB2 antagonist AM630 (Item No. ), which suggests 4-quinolone-3-carboxamide CB2 ligand may behave as an inverse agonist.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,4-
CAS Number
1314230-69-7
Synonyms
- 4Q3C CB2 Ligand
Molecular Formula
C26H34N2O3
Formula Weight
422.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 3 mg/ml
- DMSO: 3 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
λmax
230, 323 nm
SMILES
O=C(C1=CN(CCCCC)C2=C(C=CC=C2OC)C1=O)N[C@@]34CC5C[C@H](C4)C[C@H](C3)C5
InChi Code
InChI=1S/C26H34N2O3/c1-3-4-5-9-28-16-21(24(29)20-7-6-8-22(31-2)23(20)28)25(30)27-26-13-17-10-18(14-26)12-19(11-17)15-26/h6-8,16-19H,3-5,9-15H2,1-2H3,(H,27,30)/t17-,18+,19?,26?
InChi Key
YGNQQLUXHGNAEG-SJCABOPASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30573-10 |
|---|---|
| Supplier Part Number | 30573-10 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/30573m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |