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Cayman Chrysosplenetin, 5-Hydroxy-2-(4-Hydroxy-3-Methoxyphenyl)-3
Cayman Chrysosplenetin, 5-Hydroxy-2-(4-Hydroxy-3-Methoxyphenyl)-3,6,7-Trimethoxy-4h-1-Benzopyran-4-One, 10 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$266.00
Your Price
$266.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-30625-10 |
| MFG.PART: | 30625-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
20(S)-hydroxy Cholesterol is an allosteric agonist of the smoothened (Smo) receptor that activates the hedgehog (Hh) signaling pathway with an EC50 value of approxiately 3 μM in a gene transcription reporter assay using NIH3T3 cells. 20(S)-hydroxy Cholesterol is necessary for normal Hh signaling. It induces Smo accumulation in primary cilia, an early event in signaling, and binds to the extracellular, cysteine-rich domain of Smo., 20(S)-hydroxy Cholesterol also stimulates osteogenic differentiation of pluripotent bone marrow stromal cells, a process mediated via Hh and Notch signaling.,,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
cholest-5-ene-
CAS Number
516-72-3
Synonyms
- 20α-hydroxy Cholesterol
Molecular Formula
C27H46O2
Formula Weight
402.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 2 mg/mL
- DMSO: 0.1 mg/mL
- Ethanol: 20 mg/mL
- Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL
SMILES
O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@](O)(C)CCCC(C)C
InChi Code
InChI=1S/C27H46O2/c1-18(2)7-6-14-27(5,29)24-11-10-22-21-9-8-19-17-20(28)12-15-25(19,3)23(21)13-16-26(22,24)4/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t20-,21-,22-,23-,24-,25-,26-,27-/m0/s1
InChi Key
MCKLJFJEQRYRQT-APGJSSKUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30625-10 |
|---|---|
| Supplier Part Number | 30625-10 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/30625m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 603-56-5 |