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Cayman 7-Methoxycoumarin, 7-Methoxy-2h-1-Benzopyran-2-One, 5 G
Cayman 7-Methoxycoumarin, 7-Methoxy-2h-1-Benzopyran-2-One, 5 G - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$49.00
Your Price
$49.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-30857-5 |
| MFG.PART: | 30857-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
PAR3 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 1 (PAR1) and PAR2 that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR3 and residues 39-44 of the full-length human sequence. PAR3 (1-6) amide activates PAR1 and PAR2 in Jurkat and HEK cells, inducing calcium accumulation in Jurkat cells, which is reduced following desensitization with the PAR1- and PAR2-selective peptide agonist SFLLR-NH2. It decreases the expression of CDC42 in wild-type, but not PAR3 knockdown, PANC-1 cells and reduces invasion of PANC-1 cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
L-threonyl-L-
Synonyms
- Proteinase-Activated Receptor 3
- TFRGAP-NH2
Molecular Formula
C29H46N10O7 • XCF3COOH
Formula Weight
646.7
Purity
≥95%
Formulation
A solid
Solubility
- Water: 1 mg/ml
SMILES
O=C(O)C(F)(F)F.NC([C@@H]1CCCN1C([C@@H](NC(CNC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@]([C@@H](C)O)([H])N[H])=O)CC2=CC=CC=C2)=O)=O)=O)C)=O)=O
InChi Code
InChI=1S/C29H46N10O7.C2HF3O2/c1-16(28(46)39-13-7-11-21(39)24(31)42)36-22(41)15-35-25(43)19(10-6-12-34-29(32)33)37-26(44)20(14-18-8-4-3-5-9-18)38-27(45)23(30)17(2)40;3-2(4,5)1(6)7/h3-5,8-9,16-17,19-21,23,40H,6-7,10-15,30H2,1-2H3,(H2,31,42)(H,35,43)(H,36,41)(H,37,44)(H,38,45)(H4,32,33,34);(H,6,7)/t16-,17+,19-,20-,21-,23-;/m0./s1
InChi Key
APYDYKYMTBBPKU-CCCCMXJKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30857-5 |
|---|---|
| Supplier Part Number | 30857-5 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/30857m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 531-59-9 |