We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Ergosterol Peroxide, (3?,5?,8?,22e)-5,8-Epidioxy-Ergosta-6
Cayman Ergosterol Peroxide, (3?,5?,8?,22e)-5,8-Epidioxy-Ergosta-6,22-Dien-3-Ol, 500 G - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$81.00
Your Price
$81.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-30860-500 |
| MFG.PART: | 30860-500 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Ergosterol peroxide is an oxidized sterol and derivative of ergosterol (Item No. 19850) that has been found in S. aspratus and has diverse biological activities.1,2,3,4,5 It is active against the P. falciparum chloroquine-sensitive strain FCA 20/GHA with an IC50 value of 8.2 µM.2 Ergosterol peroxide (6.25-50 µM) induces apoptosis in LNCaP and DU145 prostate cancer cells.3 It inhibits growth of SNU-1 gastric, SNU-354 hepatoma, and SNU-C4 colorectal cancer cells (IC50s = 18.7, 158.2, and 84.6 µM, respectively).6 Ergosterol peroxide (60 µM) inhibits LPS-induced NF-kB DNA-binding activity and production of TNF-α in RAW 264.7 cells.4 Topical application of ergosterol peroxide reduces ear edema in a mouse model of inflammation induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) with an ID50 value of 0.2 mg/ear.5
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3β,5α,8α,22E)-
CAS Number
2061-64-5
Synonyms
- Ergosterol Endoperoxide
- NSC 31324
Molecular Formula
C28H44O3
Formula Weight
428.7
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- Methanol: soluble
SMILES
CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@@]3(OO4)C=C[C@@]54C[C@@H](O)CC[C@]5(C)[C@@]3([H])CC[C@@]21C
InChi Code
InChI=1S/C28H44O3/c1-18(2)19(3)7-8-20(4)22-9-10-23-25(22,5)13-12-24-26(6)14-11-21(29)17-27(26)15-16-28(23,24)31-30-27/h7-8,15-16,18-24,29H,9-14,17H2,1-6H3/b8-7+/t19-,20+,21-,22+,23+,24+,25+,26+,27+,28-/m0/s1
InChi Key
VXOZCESVZIRHCJ-KGHQQZOUSA-N
Origin
Plant/Unidentified sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30860-500 |
|---|---|
| Supplier Part Number | 30860-500 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/30860m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 2061-64-5 |