We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Hesperidin Methylchalconec Aurantium L Extract (Hydrate),
NETA PART: | CAYM-30884-500 |
MFG.PART: | 30884-500 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Cannabinoids (CBs) and their synthetic analogs produce biochemical and pharmacological effects by interacting with the central CB1 and peripheral CB2 receptors. The CB2 receptor has emerged as a pharmacotherapeutic target for treating osteoporosis, as well as for eliciting antinociceptive effects in various models of pain. 4-Quinolone-3-carboxamide CB2 ligand is a selective, high-affinity ligand of the CB2 receptor, displaying a Ki value of 0.6 nM (Ki >10,000 nM for CB1) in vitro. At a dose of 6 mg/kg, 4-quinolone-3-carboxamide CB2 ligand exhibits antinociceptive activity in a formalin test of nocifensive response in mice. This analgesic affect is not significantly reversed by the CB2 antagonist AM630 (Item No. ), which suggests 4-quinolone-3-carboxamide CB2 ligand may behave as an inverse agonist.
WARNING This product is not for human or veterinary use.
Technical Information
- 4Q3C CB2 Ligand
- DMF: 3 mg/ml
- DMSO: 3 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
Shipping & Storage Information
SKU | CAYM-30884-500 |
---|---|
Supplier Part Number | 30884-500 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/30884m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |