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Cayman (Des-Arg9)-Bradykinin, 1-8-Bradykinin, 25 Mg
Cayman (Des-Arg9)-Bradykinin, 1-8-Bradykinin, 25 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$414.00
Your Price
$414.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-31136-25 |
| MFG.PART: | 31136-25 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
(Des-Arg9)-Bradykinin is an active metabolite of the endogenous vasodilator bradykinin (Item No. 37408) and a peptide agonist of the bradykinin B1 receptor.1,2 It binds to bradykinin B1 and B2 receptors (Kis = 1.93 and 8.1 µM, respectively).3 (Des-Arg9)-Bradykinin is formed via carboxypeptidase-mediated cleavage of the bradykinin C-terminal arginine residue in plasma and tissues.2 It induces relaxation of precontracted isolated endothelium-denuded dog renal artery strips (pD2 = 8.6).4 (Des-Arg9)-Bradykinin decreases blood pressure in LPS-treated rabbits in a dose-dependent manner.5
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-8-bradykinin
CAS Number
15958-92-6
Synonyms
- (Des-Arg9)-BK
- (Des-Arg9)-Kallidin
- (Des-Arg9)-KD
- RPPGFSPF-OH
Molecular Formula
C44H61N11O10
Formula Weight
904.0
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 15mg/mL
- DMSO: 15mg/mL
- Ethanol: 10mg/mL
- PBS (pH 7.2): 10mg/mL
SMILES
O=C(N1CCC[C@H]1C(N2CCC[C@H]2C(NCC(N[C@H](C(N[C@@H](CO)C(N3CCC[C@H]3C(N[C@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)[C@H](CCCNC(N)=N)N[H]
InChi Code
InChI=1S/C44H61N11O10/c45-29(15-7-19-48-44(46)47)40(61)55-22-10-18-35(55)42(63)54-21-8-16-33(54)38(59)49-25-36(57)50-30(23-27-11-3-1-4-12-27)37(58)52-32(26-56)41(62)53-20-9-17-34(53)39(60)51-31(43(64)65)24-28-13-5-2-6-14-28/h1-6,11-14,29-35,56H,7-10,15-26,45H2,(H,49,59)(H,50,57)(H,51,60)(H,52,58)(H,64,65)(H4,46,47,48)/t29-,30-,31-,32-,33-,34-,35-/m0/s1
InChi Key
VCEHWDBVPZFHAG-POFDKVPJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-31136-25 |
|---|---|
| Supplier Part Number | 31136-25 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/31136m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 15958-92-6 |