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Cayman Glycoursodeoxycholic Acid-D4, N-[(3?,5?,7?)-3,7-Dihydroxy-
Cayman Glycoursodeoxycholic Acid-D4, N-[(3?,5?,7?)-3,7-Dihydroxy-24-Oxocholan-24-Yl-2,2,4,4-D4]-Glycine, 10 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$235.00
Your Price
$235.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-31309-10 |
| MFG.PART: | 31309-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Glycoursodeoxycholic acid-d4 (GUDCA-d4) is intended for use as an internal standard for the quantification of GUDCA (Item No. 21698) by GC- or LC-MS. GUDCA is a glycine-conjugated form of the secondary bile acid ursodeoxycholic acid (UDCA; Item No. 15121).1,2 It has antioxidant effects in vitro in Barrett’s esophagus cells and primary cultured rat neurons.3,4 GUDCA reduces the levels of inflammatory cytokines and prevents cell death induced by unconjugated bilirubin (Item No. 17161) in an astroglial cell model of neonatal hyperbilirubinemia.5 Oral administration of GUDCA (500 mg/kg per day) decreases the severity of symptoms and increases the amount of A. muciniphila, a commensal bacterial species commonly decreased in patients with inflammatory bowel disease (IBD), in a mouse model of colitis.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[(3α,5β,7β)-
CAS Number
2044276-17-5
Synonyms
- GUDCA-d4
- Ursodeoxycholyl Glycine-d4
Molecular Formula
C26H39D4NO5
Formula Weight
453.7
Purity
≥99% deuterated forms (d1-d4)
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: slightly soluble
- Methanol: slightly soluble
SMILES
C[C@H](CCC(NCC(O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C([2H])([2H])[C@H](O)C([2H])([2H])C[C@]4(C)[C@@]3([H])CC[C@@]21C
InChi Code
InChI=1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21+,24+,25+,26-/m1/s1/i8D2,12D2
InChi Key
GHCZAUBVMUEKKP-ODDJOPSVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-31309-10 |
|---|---|
| Supplier Part Number | 31309-10 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/31309m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CA |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 2044276-17-5 |