Cayman Prostaglandin E2-D4; Purity- Greater Than Or Equal To 99%

Cayman Prostaglandin E2-D4; Purity- Greater Than Or Equal To 99% Deuterated Forms (D1-D4); Size- 50 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)

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NETA PART:	CAYM-314010-50
MFG.PART:	314010-50
UNSPSC:	12352200
Manufacturer:	Cayman

Description

Product Description

Prostaglandin E₂-d₄ (PGE₂-d₄) contains four deuterium atoms at the 3, 3, 4, and 4 positions. It is intended for use as an internal standard for the quantification of PGE₂ by GC- or LC-mass spectrometry. PGE₂ is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation.^1,2,3,4 The effects of PGE₂ are transduced by at least four distinct receptors designated EP₁, EP₂, EP₃, and EP₄.⁵ The affinity constants (K_d) of PGE₂ for these receptors range from 1-10 nM depending on the receptor subtype and tissue.

WARNING This product is not for human or veterinary use.

Technical Information

Formal Name

9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-3,3,4,4-d₄ acid

CAS Number

34210-10-1

Synonyms

Dinoprostone-d₄
PGE₂-d₄

Molecular Formula

C₂₀H₂₈D₄O₅

Formula Weight

356.5

Purity

≥99% deuterated forms (d₁-d₄)

Formulation(Request formulation change)

A solution in methyl acetate

Solubility(Learn about Variance in Solubility)

DMF: >100 mg/ml (from PGE2)
DMSO: >100 mg/ml (from PGE2)
Ethanol: >100 mg/ml (from PGE2)
PBS pH 7.2: >5 mg/ml (from PGE2)

SMILES

O[C@H]1[C@H](/C=C/[C@@H](O)CCCCC)[C@@H](C/C=C\C([2H])([2H])C([2H])([2H])CC(O)=O)C(C1)=O

InChi Code

InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1/i5D2,8D2

InChi Key

XEYBRNLFEZDVAW-YOLMOHOWSA-N

Shipping & Storage Information

Storage

-20°C

Shipping

Wet ice in continental US; may vary elsewhere

Stability

≥ 2 years

Specifications

More Information
SKU	CAYM-314010-50
Supplier Part Number	314010-50
UM	UNIT
UNSPSC	12352200
Manufacturer	Cayman
MSDS URL	https://www.caymanchem.com/msdss/314010m.pdf
Temperature	-20
Refrigerated-Frozen	Refrigerated
CountryOfOrigin	US
ProductLine	CAYM
Qty	50
MinOrderQty	1
Weight	7.00
Lead Time	2 Business Days
Hazardous	Y
CAS Number	34210-10-1

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Cayman Prostaglandin E2-D4; Purity- Greater Than Or Equal To 99%

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Technical Information

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