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Cayman Cgs 9343b, 1,3-Dihydro-1-[1-[(4-Methyl-4h,6h-Pyrrolo[1,2-A
Cayman Cgs 9343b, 1,3-Dihydro-1-[1-[(4-Methyl-4h,6h-Pyrrolo[1,2-A][4,1]Benzoxazepin-4-Yl)Methyl]-4-Piperidinyl]-2h-Benzimidazol-2-One, 2z-Butenedioate, 1 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$37.00
Your Price
$37.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-32844-1 |
MFG.PART: | 32844-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
CGS 9343B is a calmodulin inhibitor.,, It inhibits calmodulin-induced phosphodiesterase (PDE) activity (IC50 = 3.3 µM) but does not inhibit basal PKC activity at 100 µM. CGS 9343B (120 µM) inhibits calcium release induced by inositol 1,4,5-trisphosphate (IP3) in 261B rat liver epithelial cells. It reduces the incidence of diarrhea without affecting gastrointestinal transit time in a mouse model of secretory diarrhea induced by castor oil when administered at a dose of 3 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,3-dihydro-1- [1-[(4-methyl- 4H,6H-pyrrolo [1,2-a][4,1] benzoxazepin- 4-yl)methyl]-4- piperidinyl]- 2H- benzimidazol- 2-one, 2Z- butenedioate
CAS Number
109826-27-9
Synonyms
- KW-5617
- Zaldaride Maleate
Molecular Formula
C26H28N4O2 • C4H4O4
Formula Weight
544.6
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: soluble
- Ethanol: slightly soluble, warmed
SMILES
CC1(C2=CC=CN2C3=CC=CC=C3CO1)CN4CCC(N5C(NC6=CC=CC=C65)=O)CC4.OC(/C=C\C(O)=O)=O
InChi Code
InChI=1S/C26H28N4O2.C4H4O4/c1-26(24-11-6-14-29(24)22-9-4-2-7-19(22)17-32-26)18-28-15-12-20(13-16-28)30-23-10-5-3-8-21(23)27-25(30)31;5-3(6)1-2-4(7)8/h2-11,14,20H,12-13,15-18H2,1H3,(H,27,31);1-2H,(H,5,6)(H,7,8)/b;2-1-
InChi Key
NGODOSILXOFQPH-BTJKTKAUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-32844-1 |
---|---|
Supplier Part Number | 32844-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/32844m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 109826-27-9 |