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Cayman 7-Xylosyltaxol, (2ar,4s,4as,6r,9s,11s,12s,12ar,12bs)-9-(((
Cayman 7-Xylosyltaxol, (2ar,4s,4as,6r,9s,11s,12s,12ar,12bs)-9-(((2r,3s)-3-Benzamido-2-Hydroxy-3-Phenylpropanoyl)Oxy)-12-(Benzoyloxy)-11-Hydroxy-4a,8,13,13-Tetramethyl-5-Oxo-4-(((2s,3r,4s,5r) - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$311.00
Your Price
$311.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-32956-1 |
| MFG.PART: | 32956-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
7-Xylosyltaxol is a taxane and derivative of paclitaxel (Item No. ) that has been found in T. chinensis and has microtubule disruptor and anticancer activities.,, It induces the disassembly of pig brain and Physarum microtubules in cell-free assays (IC50s = 0.2 and 0.4 µM, respectively). 7-Xylosyltaxol inhibits proliferation of A549, MCF-7, A2780, HCT-8, and SW480 cancer cells with IC50 values of 0.39, 0.16, 0.85, 5.9, and 5.6 µM, respectively.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(αR,βS)-β-(benzoylamino)-α-hydroxy-benzenepropanoic acid, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester
CAS Number
90332-66-4
Molecular Formula
C52H59NO18
Formula Weight
986.0
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: 10 mM
SMILES
C[C@]1(C([C@@H](C2=C(C)[C@@H](OC([C@H](O)[C@H](C3=CC=CC=C3)NC(C4=CC=CC=C4)=O)=O)C[C@]5(O)C2(C)C)OC(C)=O)=O)[C@@]([C@@H]5OC(C6=CC=CC=C6)=O)([H])[C@@]([C@@]7([H])C[C@@H]1O[C@@](OC[C@H]8O)([H])[C@@H]([C@H]8O)O)(CO7)OC(C)=O
InChi Code
InChI=1S/C52H59NO18/c1-26-33(68-47(63)39(58)37(29-16-10-7-11-17-29)53-45(61)30-18-12-8-13-19-30)23-52(64)44(70-46(62)31-20-14-9-15-21-31)42-50(6,43(60)41(67-27(2)54)36(26)49(52,4)5)34(22-35-51(42,25-66-35)71-28(3)55)69-48-40(59)38(57)32(56)24-65-48/h7-21,32-35,37-42,44,48,56-59,64H,22-25H2,1-6H3,(H,53,61)/t32-,33+,34+,35-,37+,38+,39-,40-,41-,42+,44+,48+,50-,51+,52-/m1/s1
InChi Key
ZVEGOBHUZTXSFK-TZIKQHFSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-32956-1 |
|---|---|
| Supplier Part Number | 32956-1 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/32956m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 90332-66-4 |