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Cayman Ns 5806; Size- 10 Mg
Cayman Ns 5806; Size- 10 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$266.00
Your Price
$266.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-33226-10 |
| MFG.PART: | 33226-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
NS 5806 is an activator of the calcium-independent transient outward potassium current (Ito).1 It increases Kv4.3-mediated Ito current amplitudes (EC50 = 5.3 µM), as well as slows Ito current decay in a manner dependent on potassium channel interaction protein 2 (KChIP2), in CHO-K1 cells expressing human Kv4.3. NS 5806 increases Ito currents in isolated rabbit ventricular myocytes (EC50 = 1.6 µM).2 It reverses rapid pacing-induced decreases in Ito current recovery and restores the spike-and-dome morphology of the epicardial action potential in ventricular wedge preparations isolated from a dog heart in a model of heart failure.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[3,5-bis
CAS Number
426834-69-7
Molecular Formula
C16H8Br2F6N6O
Formula Weight
574.1
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: 50 mg/ml
- Ethanol: 25 mg/ml
λmax
245 nm
SMILES
O=C(NC1=C(C2=NN=NN2)C=C(Br)C=C1Br)NC3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3
InChi Code
InChI=1S/C16H8Br2F6N6O/c17-8-4-10(13-27-29-30-28-13)12(11(18)5-8)26-14(31)25-9-2-6(15(19,20)21)1-7(3-9)16(22,23)24/h1-5H,(H2,25,26,31)(H,27,28,29,30)
InChi Key
UZWJWROOLOOCPQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33226-10 |
|---|---|
| Supplier Part Number | 33226-10 |
| UM | UN |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/33226m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 10 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |
| CAS Number | 426834-69-7 |