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Cayman Pnu 112455a; Qty- 25; Size-25 Mg
Cayman Pnu 112455a; Qty- 25; Size-25 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$510.00
Your Price
$510.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-33438-25 |
| MFG.PART: | 33438-25 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
PNU 112455A is an inhibitor of cyclin-dependent kinase 2 (Cdk2) and Cdk5 (Ki = 2 µM for both).1 It inhibits hyperphosphorylation of tau and cell death induced by the synthetic glucocorticoid dexamethasone (Item No. 11015) in PC12 rat adrenal medulla cells expressing human tau when used at concentrations of 1 and 10 µM.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[(6-amino-4-
CAS Number
21886-12-4
Molecular Formula
C10H11N5O2S • HCl
Formula Weight
301.8
Purity
≥95%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 10 mg/ml
- PBS (pH 7.2): 10 mg/ml
λmax
221, 255, 304 nm
SMILES
O=S(N)(C1=CC=C(NC2=CC(N)=NC=N2)C=C1)=O.Cl
InChi Code
InChI=1S/C10H11N5O2S.ClH/c11-9-5-10(14-6-13-9)15-7-1-3-8(4-2-7)18(12,16)17;/h1-6H,(H2,12,16,17)(H3,11,13,14,15);1H
InChi Key
XBXQRCJKDCEQBS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33438-25 |
|---|---|
| Supplier Part Number | 33438-25 |
| UM | UN |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/33438m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 25 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 21886-12-4 |