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Cayman (R)-Hydroxychloroquine (Sulfate); Size- 1 Mg
Cayman (R)-Hydroxychloroquine (Sulfate); Size- 1 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$138.00
Your Price
$138.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-33442-1 |
| MFG.PART: | 33442-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Lin28 1632 is a small molecule inhibitor of the interaction between the RNA binding protein Lin28 and let-7 precursor RNA (IC50 = 8 μM in a competition ELISA). It increases levels of endogenous let-7 miRNAs and decreases Lin28 expression in a dose-dependent manner in murine embryonic stem cells (mESCs). Lin28 1632 inhibits clonogenic growth of 22Rv1, PC3, DU145, and Huh7 cancer cells and decreases tumor-sphere formation by 22Rv1 and Huh7 cells in vitro. It also binds bromodomain-containing protein 4 (BRD4) and CREB-binding protein (CBP/CREBBP) bromodomains (Kds = 7 and 25 μM, respectively).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-methyl-N-
CAS Number
108825-65-6
Molecular Formula
C15H15N5O
Formula Weight
281.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- PBS (pH 7.2): 0.5 mg/ml
λmax
247, 285 nm
SMILES
CN(C(C)=O)C1=CC=CC(C(C=C2)=NN3C2=NN=C3C)=C1
InChi Code
InChI=1S/C15H15N5O/c1-10-16-17-15-8-7-14(18-20(10)15)12-5-4-6-13(9-12)19(3)11(2)21/h4-9H,1-3H3
InChi Key
WPAQLESUVYGUJZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33442-1 |
|---|---|
| Supplier Part Number | 33442-1 |
| UM | UN |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/33442m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CA |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 2488706-20-1 |