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Cayman Gba3 (Human, Recombinant), Size50 Μg, Purity≥90% Est
Cayman Gba3 (Human, Recombinant), Size - 50 Μg, Purity - ≥90% Estimated By Sds-Page - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$344.40
Your Price
$344.40
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-33991-50 |
| MFG.PART: | 33991-50 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Cytosolic β-glucosidase (GBA3) is a neutral β-glucocerebrosidase.1,2 It is composed of a single glycoside hydrolase domain and hydrolyzes glucosyl- and galactosylceramides. GBA3 is expressed in the liver, small intestine, colon, spleen, and kidneys.3 In vitro, knockdown of GBA3 inhibits mitotic arrest and promotes resistance to paclitaxel (Item No. 10461) in colon cancer cells.4 Tumor levels of GBA3 are lower in patients with hepatocellular carcinoma and decreased expression is associated with poor prognosis.5 Unlike GBA1, polymorphisms in GBA3 are not associated with Gaucher disease, a lysosomal storage disorder.6 Cayman’s GBA3 (human, recombinant) protein can be used for enzyme activity assays. This protein consists of 480 amino acids and has a calculated molecular weight of 55 kDa.
WARNING This product is not for human or veterinary use.
Technical Information
Synonyms
- cBGL1
- Cytosolic β-Glucosidase
- Cytosolic β-Glucosidase-like Protein-1
- Klotho-related Protein
- KLrP
Purity
≥90% estimated by SDS-PAGE
Endotoxin Testing
<1.0 EU/μg, determined by the LAL endotoxin assay
Source
Active recombinant human C-terminal His-tagged GBA3 expressed in insect cells
Amino Acids
1-469 (full length)
MW
55 kDa
Formulation(Request formulation change)
Lyophilized from sterile 20 mM Tris, 300 mM sodium chloride, pH 7.5, with 10% glycerol, 5% trehalose, 5% mannitol, and 0.01% tween-80
Host
Insect cells
UniProt Accession №
Q9H227
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Stability
≥ 1 year
| SKU | CAYM-33991-50 |
|---|---|
| Supplier Part Number | 33991-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -80 |
| Refrigerated-Frozen | Frozen |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |