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Cayman 5-(4,6-Dichloro-S-Triazin-2-Ylamino)Fluorescein (Hydrochloride)
Cayman 5-(4,6-Dichloro-S-Triazin-2-Ylamino)Fluorescein (Hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$143.00
Your Price
$143.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-34080-250 |
MFG.PART: | 34080-250 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
PNU 120596 is a positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor (nAChR), increasing agonist-evoked calcium flux (EC50 = 216 nM). It has no detectable effect on α4β2, α3β4, or α9β10 nAChRs. PNU-120596 increases the frequency of ACh-evoked GABAergic postsynaptic currents in rat hippocampal slices and improves the auditory gating deficit caused by amphetamine in rats., It also reduces the cortical/subcortical infarct volume caused by transient focal cerebral ischemia in rats.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(5-chloro-2,4- dimethoxyphenyl)-N’- (5-methyl-3- isoxazolyl)-urea
CAS Number
501925-31-1
Synonyms
- NSC 216666
Molecular Formula
C13H14ClN3O4
Formula Weight
311.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL
- DMSO: 20 mg/mL
λmax
210, 254, 298 nm
SMILES
ClC1=C(OC)C=C(OC)C(NC(NC2=NOC(C)=C2)=O)=C1
InChi Code
InChI=1S/C13H14ClN3O4/c1-7-4-12(17-21-7)16-13(18)15-9-5-8(14)10(19-2)6-11(9)20-3/h4-6H,1-3H3,(H2,15,16,17,18)
InChi Key
CEIIEALEIHQDBX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-34080-250 |
---|---|
Supplier Part Number | 34080-250 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/34080m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 250 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 21811-74-5 |