We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman 5(S)-Hete Lactone; Purity- Greater Than Or Equal To 98%; S
Cayman 5(S)-Hete Lactone; Purity- Greater Than Or Equal To 98%; Size- 25 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$138.00
Your Price
$138.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-34240-25 |
| MFG.PART: | 34240-25 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Ergosterol peroxide is an oxidized sterol and derivative of ergosterol (Item No. ) that has been found in S. aspratus and has diverse biological activities.,,,, It is active against the P. falciparum chloroquine-sensitive strain FCA 20/GHA with an IC50 value of 8.2 µM. Ergosterol peroxide (6.25-50 µM) induces apoptosis in LNCaP and DU145 prostate cancer cells. It inhibits growth of SNU-1 gastric, SNU-354 hepatoma, and SNU-C4 colorectal cancer cells (IC50s = 18.7, 158.2, and 84.6 µM, respectively). Ergosterol peroxide (60 µM) inhibits LPS-induced NF-kB DNA-binding activity and production of TNF-α in RAW 264.7 cells. Topical application of ergosterol peroxide reduces ear edema in a mouse model of inflammation induced by phorbol 12-myristate 13-acetate (TPA; Item No. ) with an ID50 value of 0.2 mg/ear.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3β,5α,8α,22E)-
CAS Number
2061-64-5
Synonyms
- Ergosterol Endoperoxide
- NSC 31324
Molecular Formula
C28H44O3
Formula Weight
428.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
- Methanol: soluble
SMILES
CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@@]3(OO4)C=C[C@@]54C[C@@H](O)CC[C@]5(C)[C@@]3([H])CC[C@@]21C
InChi Code
InChI=1S/C28H44O3/c1-18(2)19(3)7-8-20(4)22-9-10-23-25(22,5)13-12-24-26(6)14-11-21(29)17-27(26)15-16-28(23,24)31-30-27/h7-8,15-16,18-24,29H,9-14,17H2,1-6H3/b8-7+/t19-,20+,21-,22+,23+,24+,25+,26+,27+,28-/m0/s1
InChi Key
VXOZCESVZIRHCJ-KGHQQZOUSA-N
Origin
Plant/Unidentified sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34240-25 |
|---|---|
| Supplier Part Number | 34240-25 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/34240m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 25 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |
| CAS Number | 127708-42-3 |