We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Ganoderic Acid Dm; Qty- 1; Size-1 Mg
Cayman Ganoderic Acid Dm; Qty- 1; Size-1 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$110.00
Your Price
$110.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-34536-1 |
| MFG.PART: | 34536-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Ganoderic acid DM is a triterpenoid that has been found in G. lucidum and has diverse biological activities. 1,2,3 It inhibits 5α-reductase and HMG-CoA reductase (IC50s = 10.6 and 9.5 µM, respectively) and binds to the ligand-binding domain of the androgen receptor in a fluorescence polarization assay.1,2 Ganoderic acid suppresses osteoclastogenesis of RAW 264.7 cells when used at a concentration of 12.5 µM and is cytotoxic to K562 leukemia and PC3 prostate cancer cells (IC50s = 18.8 and 81.6 µM, respectively). It reduces ear edema induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice (ID50 = 0.08 mg/ear).3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3,7-
CAS Number
173075-45-1
Molecular Formula
C30H44O4
Formula Weight
468.7
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- Methanol: Soluble
λmax
217, 251 nm
SMILES
C[C@]12C3=C(CC[C@@]1([C@]([C@@H](CC/C=C(C)/C(O)=O)C)([H])CC2)C)[C@@]4([C@@](C(C)(C(CC4)=O)C)([H])CC3=O)C
InChi Code
InChI=1S/C30H44O4/c1-18(9-8-10-19(2)26(33)34)20-11-16-30(7)25-21(12-15-29(20,30)6)28(5)14-13-24(32)27(3,4)23(28)17-22(25)31/h10,18,20,23H,8-9,11-17H2,1-7H3,(H,33,34)/b19-10+/t18-,20-,23+,28-,29-,30+/m1/s1
InChi Key
ZTKZZRIVAYGFSF-PIPDTRPPSA-N
Origin
Plant/Unspecified sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34536-1 |
|---|---|
| Supplier Part Number | 34536-1 |
| UM | UN |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/34536m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 173075-45-1 |