We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Apiin; Qty- 10; Size-10 Mg
Cayman Apiin; Qty- 10; Size-10 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$286.00
Your Price
$286.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-34596-10 |
| MFG.PART: | 34596-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Apiin is a polyketide synthase-derived flavonoid glycoside that has been found in A. graveolens and has diverse biological activities.1,2,3,4 It inhibits Aurora B kinase in a cell-free assay using the human enzyme (IC50 = 12.14 µM).2 Apiin (10 and 50 µg/ml) inhibits LPS-induced increases in nitric oxide (NO) release and inducible nitric oxide synthase (iNOS) levels in J774.A1 macrophages.3 It scavenges DPPH (Item No. 14805), superoxide, and hydroxyl radicals (IC50s = 68, 390, and 48 µg/ml, respectively), as well as increases the levels of superoxide dismutase (SOD) and catalase in mouse serum, brain, heart, liver, and kidney when administered at a dose of 50 mg/kg.4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
7-[(2-O-D-apio-
CAS Number
26544-34-3
Synonyms
- Apigenin 7-apisoylglucoside
- Apigenin 7-O-apioglucoside
Molecular Formula
C26H28O14
Formula Weight
564.5
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
λmax
269, 338 nm
SMILES
O=C1C2=C(O)C=C(O[C@H]3[C@H](O[C@@]4([H])[C@H](O)[C@](CO)(O)CO4)[C@@H](O)[C@H](O)[C@@H](CO)O3)C=C2OC(C5=CC=C(O)C=C5)=C1
InChi Code
InChI=1S/C26H28O14/c27-8-18-20(32)21(33)22(40-25-23(34)26(35,9-28)10-36-25)24(39-18)37-13-5-14(30)19-15(31)7-16(38-17(19)6-13)11-1-3-12(29)4-2-11/h1-7,18,20-25,27-30,32-35H,8-10H2/t18-,20-,21+,22-,23+,24-,25+,26-/m1/s1
InChi Key
NTDLXWMIWOECHG-YRCFQSNFSA-N
Origin
Plant/Apium graveolens
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34596-10 |
|---|---|
| Supplier Part Number | 34596-10 |
| UM | UN |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/34596m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 10 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 26544-34-3 |