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Cayman Lipid A6
Cayman Lipid A6 - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$670.00
Your Price
$670.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-35052-25 |
| MFG.PART: | 35052-25 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Hexahydrocurcumin is a natural product and an active metabolite of curcumin. It reduces prostaglandin E2 (PGE2) production stimulated by phorbol 12-myristate 13-acetate (PMA; Item No. ) by 37% in human colonic epithelial cells when used at a concentration of 20 µM. Hexahydrocurcumin (3.125-25 µM) inhibits overproduction of nitric oxide induced by LPS in RAW 264.7 macrophage cells in a concentration-dependent manner. It does not affect LPS-induced cytokine release but inhibits LPS-induced iNOS and COX-2 upregulation and NF-κB activation when used at a concentration of 50 µM. Hexahydrocurcumin prevents the formation of aberrant crypt foci in a dimethylhydrazine rat model of colon cancer and potentiates the effect of 5-fluorouracil (Item No. ).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-hydroxy-1,7-
CAS Number
36062-05-2
Molecular Formula
C21H26O6
Formula Weight
374.4
Purity
≥95%
Formulation
A solution in ethanol
Solubility
- DMF: 10 mg/ml
- DMF:PBS(pH7.2) (1:2): 0.3 mg/ml
- DMSO: 5 mg/ml
- Ethanol: 0.25 mg/ml
λmax
279 nm
SMILES
OC1=C(OC)C=C(CCC(O)CC(CCC2=CC=C(O)C(OC)=C2)=O)C=C1
InChi Code
InChI=1S/C21H26O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,16,22,24-25H,3-4,7-8,13H2,1-2H3
InChi Key
RSAHICAPUYTWHW-UHFFFAOYSA-N
Origin
Plant/Curcuma longa
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-35052-25 |
|---|---|
| Supplier Part Number | 35052-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| ProductLine | CAYM |
| Qty | 25 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |