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Cayman Isotonitazene Uncyclized Intermediate
Cayman Isotonitazene Uncyclized Intermediate - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$71.00
Your Price
$71.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-35156-1 |
| MFG.PART: | 35156-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
A-1120 is a non-retinoid retinol binding protein 4 (RBP4) antagonist (Ki = 8.3 nM for disruption of RBP4 binding to transthyretin). It is selective for RBP4 over cellular retinol binding protein 1 (CRBP1; IC50s = 0.09 and >30 µM, respectively, in radioligand binding assays), as well as a panel of G protein-coupled receptors, kinases, and enzymes. A-1120 (30 mg/kg) reduces serum levels of RBP4 and retinol in mice. It also inhibits retinal bisretinoid accumulation in the Abca4-/- mouse model of enhanced retinal lipofuscinogenesis-induced macular degeneration.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[[[4-[2-
CAS Number
1152782-19-8
Molecular Formula
C20H19F3N2O3
Formula Weight
392.4
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMSO: 100 mM
- Ethanol: 25 mM
λmax
226, 252 nm
SMILES
FC(F)(F)C1=CC=CC=C1C2CCN(C(NC3=C(C(O)=O)C=CC=C3)=O)CC2
InChi Code
InChI=1S/C20H19F3N2O3/c21-20(22,23)16-7-3-1-5-14(16)13-9-11-25(12-10-13)19(28)24-17-8-4-2-6-15(17)18(26)27/h1-8,13H,9-12H2,(H,24,28)(H,26,27)
InChi Key
MEAQCLPMSVEOQF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-35156-1 |
|---|---|
| Supplier Part Number | 35156-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |