Cayman 3,5-Diiodo-L-Thyronine, 500mg

3,5-Diiodo-L-thyronine (3,5-T2) is a thyroid hormone metabolite.¹ It binds to thyroid hormone receptor α₁ (TRα₁), TRβ₁, and TRβ₂ (EC₅₀s = 0.8, 0.79, and 0.1 µM, respectively, in cell-free assays).² 3,5-T2 (1 pM) stimulates oxygen consumption in perfused livers isolated from rats with hypothyroidism induced by sodium iodide.³ It reduces subcutaneous and epididymal fat mass, as well as decreases serum leptin and cholesterol levels, without affecting body weight in high-fat diet-induced obese mice when administered at a dose of 2.5 µg/g per day.¹

WARNING This product is not for human or veterinary use.