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Cayman Lupenone
Cayman Lupenone - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$428.00
Your Price
$428.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-35335-10 |
| MFG.PART: | 35335-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Lupenone is a triterpenoid that has been found in L. eriocalyx and has diverse biological activities.1,2,3,4 It inhibits HIV-1 reverse transcriptase (IC50 = 2.1 μM).1 Lupenone is active against the W2 and D6 strains of P. falciparum (IC50s = 208.1 and 394.7 ng/ml, respectively).2 It induces melanogenesis in (EC50 = 0.35 µM), and inhibits the growth of, B16 2F2 melanoma cells in vitro (IC50 = 25.4 µM).3 Topical application of lupenone (1 mg/ear) reduces ear edema induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice.4 It also inhibits acetic acid-induced writhing in mice when administered at a dose of 100 mg/kg.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
lup-20(29)-
CAS Number
1617-70-5
Synonyms
- NSC 281807
Molecular Formula
C30H48O
Formula Weight
424.7
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 2 mg/mL
- DMSO: Slightly soluble
- Ethanol: Slightly soluble
SMILES
C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]4([H])[C@@]3(CCC(C4(C)C)=O)C)C)([H])[C@]5([H])[C@@](CC1)(CC[C@H]5C(C)=C)C
InChi Code
InChI=1S/C30H48O/c1-19(2)20-11-14-27(5)17-18-29(7)21(25(20)27)9-10-23-28(6)15-13-24(31)26(3,4)22(28)12-16-30(23,29)8/h20-23,25H,1,9-18H2,2-8H3/t20-,21+,22-,23+,25+,27+,28-,29+,30+/m0/s1
InChi Key
GRBHNQFQFHLCHO-BHMAJAPKSA-N
Origin
Plant/Adenophora tetraphylla
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-35335-10 |
|---|---|
| Supplier Part Number | 35335-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/35335m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 10 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1617-70-5 |