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Cayman Lipid Nanoparticle (Lnp-0315) Exploration Kit, 1ea
Cayman Lipid Nanoparticle (Lnp-0315) Exploration Kit, 1ea - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$264.00
Your Price
$264.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-35426-1 |
| MFG.PART: | 35426-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 µM; IC50 = 1-5 µM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 µM) as well as the serine/threonine protein phosphatase CAPP at concentrations up to 10 µM. D-erythro-MAPP increases intracellular ceramide levels, induces cell cycle arrest at the G0/G1 phase, and inhibits growth of HL-60 promyelocytic leukemia cells in a time- and concentration-dependent manner.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-
CAS Number
143492-38-0
Synonyms
- (1S,2R-
D- erythro- 2- N- myristoylamino)- 1- phenyl- 1- propanol
Molecular Formula
C23H39NO2
Formula Weight
361.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/ml
- DMSO: .1 mg/ml
- Ethanol: 20 mg/ml
- Ethanol:PBS (pH 7.2) (1:2): .5 mg/ml
SMILES
O[C@H]([C@H](N(C(CCCCCCCCCCCCC)=O)[H])C)C1=CC=CC=C1
InChi Code
InChI=1S/C23H39NO2/c1-3-4-5-6-7-8-9-10-11-12-16-19-22(25)24-20(2)23(26)21-17-14-13-15-18-21/h13-15,17-18,20,23,26H,3-12,16,19H2,1-2H3,(H,24,25)/t20-,23-/m1/s1
InChi Key
YLAZEWZHIRBZDA-NFBKMPQASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-35426-1 |
|---|---|
| Supplier Part Number | 35426-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/35426m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |