Cayman Recombinant Prokaryotic Lectin-Αgal (P. Aeruginosa)

Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Five subtypes (M_1-5) have been identified, which preferentially couple to various effector systems based on their G protein interaction.^,Tropicamide is a muscarinic acetylcholine receptor (mAChR) antagonist (pK_i = 7.2 in chicken heart) that displays 3-fold selectivity for M₄.^,, When applied as eye drops, it produces temporary mydriasis (pupil dilation; EC₅₀ = 6 µg/ml) and cycloplegia (ciliary muscle paralysis; EC₅₀ = 25 µg/ml). Tropicamide has been used to probe mAChR activity in a mouse model of fragile X syndrome.

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