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Cayman Isomeranzin
Cayman Isomeranzin - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$354.00
Your Price
$354.00
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| NETA PART: | CAYM-35827-10 |
| MFG.PART: | 35827-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Erythromycin-13C-d3 is intended for use as an internal standard for the quantification of erythromycin (Item No. ) by GC- or LC-MS. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is active against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s = 0.015-2.0 mg/l). Erythromycin (10-40 mg/kg) dose-dependently inhibits the growth of S. aureus in a mouse model of thigh infection. It also inhibits the cytochrome P450 (CYP450) isoform CYP3A4 in vitro with IC50 values of 33 and 27.3 µM for α-hydroxytriazolam and 4-hydroxytriazolam formation, respectively, following administration of triazolam, which is known to be metabolized primarily by CYP3A4., Formulations containing erythromycin have been used in the treatment of bacterial respiratory and skin infections, pertussis, and a variety of other bacterial infections.
WARNING This product is not for human or veterinary use.
Technical Information
| Formal Name | (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,3R,4S,6R)-3-hydroxy-6-methyl-4-(methyl(methyl-13C-d3)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione |
| CAS Number | 2378755-50-9 |
| Molecular Formula | C36[13C]H64D3NO13 |
| Formula Weight | 738.0 |
| Purity | ≥99% deuterated forms (d1-d3) |
| Formulation | A solid |
| Solubility |
|
| SMILES | C[C@H]1[C@H](O)[C@@](OC)(C)C[C@@](O[C@H]([C@@H](C)C(O[C@H](CC)[C@]([C@H](O)[C@H]2C)(O)C)=O)[C@H](C)[C@@H](O[C@@]3([H])[C@H](O)[C@@H](N(C)[13C]([2H])([2H])[2H])C[C@@H](C)O3)[C@](C)(O)C[C@@H](C)C2=O)([H])O1 |
| InChi Code | InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1/i11+1D3 |
| InChi Key | ULGZDMOVFRHVEP-ZZKXWFBHSA-N |
| Storage | -20°C |
| Shipping | Room Temperature in continental US; may vary elsewhere |
| Stability | ≥ 4 years |
| SKU | CAYM-35827-10 |
|---|---|
| Supplier Part Number | 35827-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/35827m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 10 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1088-17-1 |