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Cayman TTAPE-Me
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![](https://netam2po.netascientific.info/media/skin/seal.png)
NETA PART: | CAYM-36068-10 |
MFG.PART: | 36068-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Atomoxetine-d3 is intended for use as an internal standard for the quantification of atomoxetine (Item No. ) by GC- or LC-MS. Atomoxetine is a selective norepinephrine reuptake inhibitor with Ki values of 5, 77, and 1,451 nM for norepinephrine, serotonin, and dopamine transporters, respectively. It is selective over the choline, GABA, and adenosine transporters, and a number of neurotransmitter receptors, ion channels, second messengers, and brain/gut peptides. In the rat prefrontal cortex (PFC), it increases extracellular norepinephrine and dopamine by 3-fold and increases Fos expression. Atomoxetine (0.1, 0.5, and 1 mg/kg) reduces premature responding, a measure of impulsivity, by rats in the 5-choice serial reaction time test (5CRTT) in a dose-dependent manner. It also has neuroprotective effects when administered prior to ischemic damage in a gerbil model of transient cerebral ischemia. Formulations containing atomoxetine have been used in the treatment of attention-deficit hyperactivity disorder (ADHD) in children, adolescents, and adults.
WARNING This product is not for human or veterinary use.
Technical Information
- Chloroform: slightly soluble
- Methanol: slightly soluble
Shipping & Storage Information
SKU | CAYM-36068-10 |
---|---|
Supplier Part Number | 36068-10 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |