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Cayman Flavokawain A
NETA PART: | CAYM-36083-5 |
MFG.PART: | 36083-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
4-Aminobenzoic acid hydrazide (4-ABAH) is an irreversible inhibitor of myeloperoxidase (MPO; IC50 = 0.3 µM). It reduces the production of hypochlorous acid (HOCl) induced by opsonized zymosan or phorbol 12-myristate 13-acetate (PMA; Item No. ) in isolated human neutrophils with IC50 values of 16 and 2.2 µM, respectively. 4-ABAH inhibits PMA-induced formation of neutrophil extracellular traps (NETs) in the same cells. It reduces infarct volume and the severity of neurological deficits, as well as increases survival, in a mouse model of cerebral ischemia induced by transient middle cerebral artery occlusion (MCAO) when administered at a dose of 40 mg/kg twice per day.
WARNING This product is not for human or veterinary use.
Technical Information
- 4-
ABAH - Myeloperoxidase Inhibitor 1
- NSC 640
- DMF: 10 mg/ml
- DMSO: 14 mg/ml
- DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
Shipping & Storage Information
SKU | CAYM-36083-5 |
---|---|
Supplier Part Number | 36083-5 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/36083m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 37951-13-6 |