Cayman Taraxasterol Acetate; 5 Mg; 6426-43-3; ≥95%

Taraxasterol acetate is a pentacyclic triterpene that has been found in P. sagittalis and has diverse biological activities.^1,2 It reduces the production of reactive oxygen species (ROS) and Hsp72 induced by phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in isolated human neutrophils when used at concentrations of 10 and 100 µM and increases Hsp72 production in unstimulated isolated human neutrophils at 100 µM.¹ Taraxasterol acetate (50 µg/ml) reduces protein levels of the E3 ubiquitin ligase RNF31 and increases levels of the autophagy marker LC3-I/II in HCT116 and SW480 cells.² Topical administration of taraxasterol acetate (46 µg/ear) reduces ear edema induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607), croton oil, or PMA in mice.¹

WARNING This product is not for human or veterinary use.