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Cayman Lc10; 25 Mg; ≥98%
NETA PART: | CAYM-37000-25 |
MFG.PART: | 37000-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
LC10 is a lipidoid derivative of the secondary bile acid lithocholic acid (Item No. 20253) that contains two 10-carbon alkyl chains.1 It has been used in the generation of self-assembling skin-permeable lipid nanoparticles (LNPs). LC10 LNPs inhibit the proliferation of normal human epidermal keratinocytes (NHEKs) when used at a concentration of 100 nM and reduce the levels of TNF-α, IL-17, and IL-23 in human peripheral blood mononuclear cells (PBMCs) at 50, 100, and 200 nM. Topical application of LC10 LNPs (10 mg/kg) reduces psoriatic-like plaques and reverses weight loss induced by imiquimod (Item No. 14956) in a mouse model of psoriasis.
WARNING This product is not for human or veterinary use.
Technical Information
- Ethanol: 100 mg/ml
Shipping & Storage Information
SKU | CAYM-37000-25 |
---|---|
Supplier Part Number | 37000-25 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
ProductLine | CAYM |
Qty | 25 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |