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Cayman 306-O12b-3; 25 Mg; ≥95%
NETA PART: | CAYM-37096-25 |
MFG.PART: | 37096-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
306-O12B-3 is an ionizable cationic lipidoid.1 It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of antisense oligonucleotides (ASOs). LNPs containing 306-O12B-3 localize to the liver after intravenous administration in mice. LNPs containing 306-O12B-3 in combination with other lipids encapsulating ASOs targeting the gene encoding proprotein convertase subtilisin kexin type 9 (PCSK9) decrease hepatic PCSK9 expression in mice. Intravenous administration of LNPs containing 306-O12B-3 and the cationic lipidoid NT1-O14B (Item No. 37095) encapsulating ASOs against tau decreases tau expression and levels in mouse brain.2
WARNING This product is not for human or veterinary use.
Technical Information
- Ethanol: 10 mg/ml
Shipping & Storage Information
SKU | CAYM-37096-25 |
---|---|
Supplier Part Number | 37096-25 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
ProductLine | CAYM |
Qty | 25 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |