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Cayman Itgal/Cd11a Chimeric Monoclonal Antibody; 200 Μg;
NETA PART: | CAYM-37155-200 |
MFG.PART: | 37155-200 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
CD11a, also known as integrin αL (ITGAL), is a protein subunit of the heterodimeric leukocyte integrin αLβ2.1 It is composed of an extracellular domain that contains an I-domain and a metal-binding domain, which are important for binding, a transmembrane region, and a short cytoplasmic tail.2 CD11a is expressed ubiquitously on the surface of leukocytes as a component of αLβ2, which binds to intracellular adhesion molecule 1-5 (ICAM-1-5), junctional adhesion molecule A (JAM-A), and endothelial cell-specific molecule 1 (ESM-1) to facilitate T cell adhesion and migration during extravasation into the lymph nodes and tissue.3 SNPs in ITGAL are associated with a reduced susceptibility to Behҫet’s disease, a systemic inflammatory disease.4 Cayman’s ITGAL/CD11a Chimeric Monoclonal Antibody (Clone hu1124 (Efalizumab)) was recombinantly generated based on the sequence of the original humanized anti-CD11a antibody hu1124.5 It can be used for flow cytometry (FC).
WARNING This product is not for human or veterinary use.
Technical Information
- CD11 Antigen-like Family Member A
- Integrin subunit αL
- ITGAL
- Leukocyte Adhesion Glycoprotein LFA-1 α chain
- LFA-1A
Shipping & Storage Information
SKU | CAYM-37155-200 |
---|---|
Supplier Part Number | 37155-200 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
ProductLine | CAYM |
Qty | 200 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |