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Cayman 3-Amino-3-deoxyadenosine-5-O-triphosphate (sodium salt)
Cayman 3-Amino-3-deoxyadenosine-5-O-triphosphate (sodium salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$434.00
Your Price
$434.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-38364-2.5 |
MFG.PART: | 38364-2.5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Proteins can be modified post-translationally by the addition of O-linked N-acetylglucosamine (O-GlcNAc). Nuclear cytoplasmic O-GlcNAcase and acetyltransferase (NCOAT) is a β-N-acetylglucosaminidase that removes GlcNAc from O-glycosylated proteins. PUGNAc is a (phenylcarbamoyl)oxime analog of GlcNAc that reversibly inhibits NCOAT (Ki = 40-110 nM)., It also less potently inhibits other hexosaminidases and exochitinases.,, (Z)-PUGNAc is a stereoisomer of PUGNAc that is a more potent inhibitor of NCOAT than the (E) isomer, both in vitro and in cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(1Z)-δ-lactone-2-(acetylamino)-2-deoxy-N-[[(phenylamino)carbonyl]oxy]-D-gluconimidic acid
CAS Number
132489-69-1
Molecular Formula
C15H19N3O7
Formula Weight
353.3
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/ml
- DMSO: 1 mg/ml
- PBS (pH 7.2): 1 mg/ml
λmax
236 nm
SMILES
O=C(C)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O/C1=N\OC(NC2=CC=CC=C2)=O
InChi Code
InChI=1S/C15H19N3O7/c1-8(20)16-11-13(22)12(21)10(7-19)24-14(11)18-25-15(23)17-9-5-3-2-4-6-9/h2-6,10-13,19,21-22H,7H2,1H3,(H,16,20)(H,17,23)/b18-14-/t10-,11-,12-,13-/m1/s1
InChi Key
PBLNJFVQMUMOJY-JXZOILRNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-38364-2.5 |
---|---|
Supplier Part Number | 38364-2.5 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
Temperature | -80 |
Refrigerated-Frozen | Frozen |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |