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Cayman AP-1
NETA PART: | CAYM-38875-5 |
MFG.PART: | 38875-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
NS 5806 is an activator of the calcium-independent transient outward potassium current (Ito). It increases Kv4.3-mediated Ito current amplitudes (EC50 = 5.3 µM), as well as slows Ito current decay in a manner dependent on potassium channel interaction protein 2 (KChIP2), in CHO-K1 cells expressing human Kv4.3. NS 5806 increases Ito currents in isolated rabbit ventricular myocytes (EC50 = 1.6 µM). It reverses rapid pacing-induced decreases in Ito current recovery and restores the spike-and-dome morphology of the epicardial action potential in ventricular wedge preparations isolated from a dog heart in a model of heart failure.
WARNING This product is not for human or veterinary use.
Technical Information
- DMSO: 50 mg/ml
- Ethanol: 25 mg/ml
Shipping & Storage Information
SKU | CAYM-38875-5 |
---|---|
Supplier Part Number | 38875-5 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |