Cayman Substance P Ache Tracer; Size- 500 Dtn

Ritanserin is a selective antagonist of the serotonin (5-HT) receptor subtype, 5-HT_2A. In a radioligand binding assay, ritanserin exhibits high selectivity for 5-HT_2A over 5-HT₁ receptors (IC₅₀s = 0.9 nM and >1000 nM, respectively). It also demonstrates relatively low affinity for histamine H₁, dopamine D₂, α₁-adrenergic, and α₂-adrenergic receptors (39-, 77-, 107-, and 166-fold lower relative to 5-HT_2A, respectively). Ritanserin (2.5 mg/kg) is long-acting, occupying >70% of 5-HT_2A sites up to 48 hours following subcutaneous administration to rats and guinea pigs. In vivo, ritanserin (10 mg/kg) blocks 5-hydroxy tryptophan-induced head twitches in rats.

WARNING This product is not for human or veterinary use.