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Cayman O-Propargyl-Puromycin Stock Solution; Size- 25 Microliters
Cayman O-Propargyl-Puromycin Stock Solution; Size- 25 Microliters; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$291.00
Your Price
$291.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-601101-25 |
| MFG.PART: | 601101-25 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Olanzapine-d8 is intended for use as an internal standard for the quantification of olanzapine (Item No. ) by GC- or LC-MS. Olanzapine is an atypical antipsychotic that binds to dopamine D1, D2, and D4 receptors (Kis = 31, 11, and 27 nM, respectively) as well as the serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT2C, and 5-HT3 (Kis = 4, 11, and 57 nM, respectively). It also binds to M1 muscarinic acetylcholine, α1-adrenergic, and histamine H1 receptors (Kis = 2, 19, and 7 nM, respectively). Olanzapine (0.5 mg/kg, i.p.) decreases immobility time in the forced swim test in non-stressed and prenatally-stressed rats, indicating antidepressant-like activity. It also decreases the number of avoidances made in the conditioned avoidance response test in rats when administered at doses of 0.5 and 1 mg/kg. Formulations containing olanzapine have been used in the treatment of schizophrenia and bipolar disorder.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-methyl-4-
CAS Number
1093380-13-2
Molecular Formula
C17H12D8N4S
Formula Weight
320.5
Purity
≥99% deuterated forms (d1-d8)
Formulation
A solid
Solubility
- DMF: 20 mg/ml
- DMSO: 15 mg/ml
- Ethanol: 1 mg/ml
SMILES
CN(C([2H])([2H])C1([2H])[2H])C([2H])([2H])C([2H])([2H])N1C2=NC3=CC=CC=C3NC4=C2C=C(C)S4
InChi Code
InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3/i7D2,8D2,9D2,10D2
InChi Key
KVWDHTXUZHCGIO-UFBJYANTSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-601101-25 |
|---|---|
| Supplier Part Number | 601101-25 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/601101m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 25 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |