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Cayman Sirt2 Direct Assay Buffer (10x); Size- 1 Ea
Cayman Sirt2 Direct Assay Buffer (10x); Size- 1 Ea; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$15.00
Your Price
$15.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-700281-1 |
| MFG.PART: | 700281-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Peroxisome proliferator-activated receptor γ (PPARγ) is activated by the anti-diabetes drugs known as thiazolidinediones, including rosiglitazone (Item No. ) and pioglitazone (Item No. ). Phosphorylation of PPARγ by cyclin-dependent kinase 5 (Cdk5) causes dysregulation of genes whose expression is altered in obesity, including adiponectin. SR 1824 is a non-agonist PPARγ ligand (Ki = 10 nM) which blocks Cdk5-mediated phosphorylation. It does not inhibit activation of PPARγ by rosiglitazone (Item No. ).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(S)-4-((5-((1-
CAS Number
1338259-06-5
Molecular Formula
C33H29BrN2O3
Formula Weight
581.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
λmax
252 nm
SMILES
BrC1=CC=C([C@H](C)NC(C2=CC=C(N(CC3=CC=C(C4=CC=CC=C4C(O)=O)C=C3)C(C)=C5C)C5=C2)=O)C=C1
InChi Code
InChI=1S/C33H29BrN2O3/c1-20-22(3)36(19-23-8-10-25(11-9-23)28-6-4-5-7-29(28)33(38)39)31-17-14-26(18-30(20)31)32(37)35-21(2)24-12-15-27(34)16-13-24/h4-18,21H,19H2,1-3H3,(H,35,37)(H,38,39)/t21-/m0/s1
InChi Key
HBMXDCXJXYASGW-NRFANRHFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-700281-1 |
|---|---|
| Supplier Part Number | 700281-1 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/700281m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |