We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman 1-Benzylimidazole, 1-(Phenylmethyl)-1h-Imidazole, 25 G
Cayman 1-Benzylimidazole, 1-(Phenylmethyl)-1h-Imidazole, 25 G - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$105.00
Your Price
$105.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-70510-25 |
MFG.PART: | 70510-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
AP-III-a4 is a small molecule enolase inhibitor (IC50 = 0.576 µM) that inhibited cancer cell metastasis in an in vivo zebrafish cancer cell xenograft model. It also reduced hyperglycemia and hyperlipidemia in C57BL/Ksj-db/db mice, a transgenic model of type 2 diabetes. Another study found that AP-III-a4 did not directly block enolase activity in vitro and suggested the mechanism is indirect.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[2-[2-(2- aminoethoxy) ethoxy]ethyl] -4-[[4- [(cyclohexyl methyl)amino] -6-[[(4- fluorophenyl) methyl]amino] -1,3,5- triazin-2-yl] amino]- benzene acetamide
CAS Number
1177827-73-4
Synonyms
- ENOblock
Molecular Formula
C31H43FN8O3
Formula Weight
594.7
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
λmax
211, 268 nm
SMILES
FC(C=C1)=CC=C1CNC2=NC(NC3=CC=C(CC(NCCOCCOCCN)=O)C=C3)=NC(NCC4CCCCC4)=N2
InChi Code
InChI=1S/C31H43FN8O3/c32-26-10-6-25(7-11-26)22-36-30-38-29(35-21-24-4-2-1-3-5-24)39-31(40-30)37-27-12-8-23(9-13-27)20-28(41)34-15-17-43-19-18-42-16-14-33/h6-13,24H,1-5,14-22,33H2,(H,34,41)(H3,35,36,37,38,39,40)
InChi Key
MOVYITHKOHMLHC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-70510-25 |
---|---|
Supplier Part Number | 70510-25 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/70510m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 4238-71-5 |