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Cayman Hydroxymethyl Uracil; Purity- Greater Than Or Equal To 98%
Cayman Hydroxymethyl Uracil; Purity- Greater Than Or Equal To 98%; Size- 250 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$12.00
Your Price
$12.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-89360-250 |
| MFG.PART: | 89360-250 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. ) and docosahexaenoic acid (DHA; Item No. ). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D1 (RvD1) is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase. A 17(R)-epimer (Item No. ) of RvD1 can also be generated in aspirin-treated samples. Both RvD1 and its 17(R)-configuration reduce human polymorphonuclear leukocyte (PMNL) transendothelial migration, the earliest event in acute inflammation, with EC50 values of ~30 nM. RvD1 and its aspirin-triggered form also exhibit a dose-dependent reduction in leukocyte infiltration in a mouse model of peritonitis with a maximal inhibition of ~35% at a 10-100 ng dose.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
7S,8R,17S-
CAS Number
872993-05-0
Synonyms
- 17(S)-
Resolvin D1 - RvD1
Molecular Formula
C22H32O5
Formula Weight
376.5
Purity
≥95%
Formulation
A solution in ethanol
Solubility
- DMF: 50 mg/ml
- Ethanol: 50 mg/ml
- PBS (pH 7.2): 0.05 mg/ml
λmax
302 nm
SMILES
CC/C=C\C[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)C/C=C\CCC(O)=O
InChi Code
InChI=1S/C22H32O5/c1-2-3-9-14-19(23)15-10-6-4-5-7-11-16-20(24)21(25)17-12-8-13-18-22(26)27/h3-12,15-16,19-21,23-25H,2,13-14,17-18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,12-8-,15-10+,16-11+/t19-,20+,21-/m0/s1
InChi Key
OIWTWACQMDFHJG-CCFUIAGSSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Stability
≥ 1 year
| SKU | CAYM-89360-250 |
|---|---|
| Supplier Part Number | 89360-250 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/89360m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 250 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 4433-40-3 |