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Cayman Jwh 122 8-Methylnaphthyl Isomer; Purity- Greater Than Or E
Cayman Jwh 122 8-Methylnaphthyl Isomer; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$270.00
Your Price
$270.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-9001037-5 |
| MFG.PART: | 9001037-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
SB939 is a pan-inhibitor of histone deacetylases (HDACs; Kis = 16-247 nM for HDAC1-11). It inhibits proliferation of A2780, COLO 205, HCT116, and PC3 cancer cells (IC50s = 0.48, 0.56, 0.48, and 0.34 µM, respectively). SB939 (50 and 100 mg/kg) reduces tumor growth and increases survival in an HCT116 mouse xenograft model. It synergizes with pacritinib (Item No. 16709) to decrease the number of metastases in a MOLM-13 mouse xenograft model when administered at a dose of 75 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-
CAS Number
929016-96-6
Synonyms
- Pracinostat
Molecular Formula
C20H30N4O2
Formula Weight
358.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 5 mg/ml
- Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
λmax
249, 303 nm
SMILES
CCN(CC)CCN1C2=C(N=C1CCCC)C=C(/C=C/C(NO)=O)C=C2
InChi Code
InChI=1S/C20H30N4O2/c1-4-7-8-19-21-17-15-16(10-12-20(25)22-26)9-11-18(17)24(19)14-13-23(5-2)6-3/h9-12,15,26H,4-8,13-14H2,1-3H3,(H,22,25)/b12-10+
InChi Key
JHDKZFFAIZKUCU-ZRDIBKRKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-9001037-5 |
|---|---|
| Supplier Part Number | 9001037-5 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/9001037m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 5 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |