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Cayman (R)-()-Linoleyl-1-Hydroxy-2-Propylamide; Purity- Greater
Cayman (R)-()-Linoleyl-1-Hydroxy-2-Propylamide; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$356.00
Your Price
$356.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-9001233-5 |
| MFG.PART: | 9001233-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
SR 18292 is an inhibitor of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α), a coactivator of transcription factors for genes involved in gluconeogenesis. SR 18292 (20 µM) increases acetylation of PGC-1α and, subsequently, decreases mRNA expression of phosphoenolpyruvate carboxykinase 1 (PEPCK1/Pck1) and the glucose-6-phosphatase catalytic subunit (G6Pc) in primary hepatocytes following stimulation with glucagon. In a dietary model of type II diabetes mellitus in mice, SR 18292 (45 mg/kg, i.p., for four days) reduces fasting blood glucose levels and the expression of liver Pck1. It also enhances glucose tolerance and insulin sensitivity in two mouse models of obesity.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[(1,1-
CAS Number
2095432-55-4
Molecular Formula
C23H30N2O2
Formula Weight
366.5
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMSO: 25 mg/ml
- DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml
- Ethanol: 10 mg/ml
λmax
217, 267, 289 nm
SMILES
CC(C)(C)N(CC(O)COC1=CC=CC2=C1C=CN2)CC3=CC=C(C)C=C3
InChi Code
InChI=1S/C23H30N2O2/c1-17-8-10-18(11-9-17)14-25(23(2,3)4)15-19(26)16-27-22-7-5-6-21-20(22)12-13-24-21/h5-13,19,24,26H,14-16H2,1-4H3
InChi Key
BNRANURXPKRRKP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-9001233-5 |
|---|---|
| Supplier Part Number | 9001233-5 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/9001233m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 5 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |
| CAS Number | 220556-74-1 |