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Cayman 4-Mapb (Hydrochloride); Purity- Greater Than Or Equal To 9
Cayman 4-Mapb (Hydrochloride); Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$81.00
Your Price
$81.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-9002103-1 |
MFG.PART: | 9002103-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
(R)-Crizotinib-d5 is intended for use as an internal standard for the quantification of (R)-crizotinib (Item No. ) by GC- or LC-MS. (R)-Crizotinib is a derivative of aminopyridine that acts as a potent, orally bioavailable, ATP-competitive small-molecule dual inhibitor of c-MET (IC50 = 8 nM) and ALK (IC50 = 20 nM) receptor tyrosine kinases. (R)-Crizotinib shows antitumor efficacy, including cytoreductive antitumor activity, in multiple tumor models implanted in athymic mice that express activated c-MET or ALK fusion proteins (IC50s = 5-20 nM).,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-[(1R)-1-(2, 6-dichloro-3- fluorophenyl) ethoxy]-5-[1- (4-piper idinyl-3,3,4, 5,5-d5)-1H- pyrazol-4- yl]-2-pyridin amine
CAS Number
1395950-84-1
Molecular Formula
C21H17Cl2D5FN5O
Formula Weight
455.4
Purity
≥99% deuterated forms (d1-d5)
Formulation
A solid
Solubility
- Chloroform: soluble
SMILES
NC1=C(O[C@@H](C2=C(Cl)C=CC(F)=C2Cl)C)C=C(C3=CN(C4([2H])C([2H])([2H])CNCC4([2H])[2H])N=C3)C=N1
InChi Code
InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1/i4D2,5D2,15D
InChi Key
KTEIFNKAUNYNJU-LJIFSARKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-9002103-1 |
---|---|
Supplier Part Number | 9002103-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/9002103m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |