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Cayman Human Macrophage Colony-Stimulating Factor Receptor Reporter Assay System
Cayman Human Macrophage Colony-Stimulating Factor Receptor Reporter Assay System - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$2,535.75
Your Price
$2,535.75
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-40068-384 |
| MFG.PART: | 40068-384 |
| UNSPSC: | 41106513 |
| Manufacturer: | Cayman |
Product Description
BMS-806 is a small molecule that inhibits the first step of HIV-1 infection by blocking the binding of host cell CD4 with viral gp120 protein. It binds the exterior envelope glycoprotein gp120 (Kd= 21.1 nM; Ki = 24.9 nM), blocking the conformational change that occurs with CD4 binding and preventing fusion of the viral and target cell membranes.,, BMS-806 is specific to HIV-1 irrespective of chemokine receptor preference, with no activity against HIV-2, SIV, or a panel of additional viruses.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[(2R)-4-benzoyl-2-methyl-1-piperazinyl]-2-
CAS Number
357263-13-9
Synonyms
- BMS-378806
Molecular Formula
C22H22N4O4
Formula Weight
406.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 12 mg/mL
- DMSO: 12 mg/mL
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL
λmax
245 nm
SMILES
O=C(N1C[C@@H](C)N(C(C(C2=CNC3=C2C(OC)=CC=N3)=O)=O)CC1)C4=CC=CC=C4
InChi Code
InChI=1S/C22H22N4O4/c1-14-13-25(21(28)15-6-4-3-5-7-15)10-11-26(14)22(29)19(27)16-12-24-20-18(16)17(30-2)8-9-23-20/h3-9,12,14H,10-11,13H2,1-2H3,(H,23,24)/t14-/m1/s1
InChi Key
OKGPFTLYBPQBIX-CQSZACIVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-40068-384 |
|---|---|
| Supplier Part Number | 40068-384 |
| UM | EA |
| UNSPSC | 41106513 |
| Manufacturer | Cayman |
| Temperature | -80 |
| Refrigerated-Frozen | Frozen |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |