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Cayman EZ Cap™ EGFP mRNA (mo5U)
Cayman EZ Cap™ EGFP mRNA (mo5U) - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$1,440.60
Your Price
$1,440.60
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-39800-1 |
| MFG.PART: | 39800-1 |
| UNSPSC: | 12352202 |
| Manufacturer: | Cayman |
Product Description
MRT67307 is a kinase inhibitor that has been shown to inhibit TBK1, MARK1-4, IKKε, and NUAK1 (IC50 values are 19, 27-52, 160, and 230 nM, respectively), the salt-inducible kinases (SIKs; IC50s = 250, 67, and 430 nM for SIK1, SIK2, and SIK3, respectively) and ULK1 and ULK2 (IC50s = 45 and 38 nM, respectively).,,, MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-β and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophages., Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[3-[[5-cyclo
Molecular Formula
C26H36N6O2 • XHCl
Formula Weight
464.6
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/ml
- DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml
- DMSO: 3 mg/ml
- Ethanol: 2 mg/ml
λmax
271 nm
SMILES
O=C(C1CCC1)NCCCNC2=NC(NC3=CC(CN4CCOCC4)=CC=C3)=NC=C2C5CC5.Cl
InChi Code
InChI=1S/C26H36N6O2.ClH/c33-25(21-5-2-6-21)28-11-3-10-27-24-23(20-8-9-20)17-29-26(31-24)30-22-7-1-4-19(16-22)18-32-12-14-34-15-13-32;/h1,4,7,16-17,20-21H,2-3,5-6,8-15,18H2,(H,28,33)(H2,27,29,30,31);1H
InChi Key
YBZGSNFTJJTIIO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-39800-1 |
|---|---|
| Supplier Part Number | 39800-1 |
| UM | EA |
| UNSPSC | 12352202 |
| Manufacturer | Cayman |
| Temperature | -80 |
| Refrigerated-Frozen | Frozen |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |