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Cayman UCB 9260
Cayman UCB 9260 - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$204.00
Your Price
$204.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-37336-10 |
| MFG.PART: | 37336-10 |
| UNSPSC: | 12352100 |
| Manufacturer: | Cayman |
Product Description
SU 16f is a potent inhibitor of platelet-derived growth factor receptor β (PDGFRβ) with an IC50 value of 10 nM. It also inhibits VEGF receptor 2 (VEGFR2; IC50 = 140 nM). SU 16f selectively inhibits PDGF- over VEFG-, FGF-, and EGF-induced cell proliferation (IC50s = 0.11, 10, 10, and 21.9 μM, respectively). It also accelerates downregulation of fibroblast genes and increases the yield of beating clusters in human foreskin fibroblasts (HFFs) treated with 15 compounds to induce a cardiac myocyte-like phenotype.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-[(1,2-di
CAS Number
251356-45-3
Synonyms
- PDGFR Tyrosine Kinase Inhibitor VII
Molecular Formula
C24H22N2O3
Formula Weight
386.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: <100mM
λmax
291, 459 nm
SMILES
O=C(N1)/C(C(C1=C2)=CC=C2C3=CC=CC=C3)=C\C4=C(C)C(CCC(O)=O)=C(C)N4
InChi Code
InChI=1S/C24H22N2O3/c1-14-18(10-11-23(27)28)15(2)25-21(14)13-20-19-9-8-17(12-22(19)26-24(20)29)16-6-4-3-5-7-16/h3-9,12-13,25H,10-11H2,1-2H3,(H,26,29)(H,27,28)/b20-13-
InChi Key
APYYTEJNOZQZNA-MOSHPQCFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-37336-10 |
|---|---|
| Supplier Part Number | 37336-10 |
| UM | EA |
| UNSPSC | 12352100 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/37336m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1515888-53-5 |