We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Flavokawain C
Cayman Flavokawain C - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$253.00
Your Price
$253.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-39393-5 |
| MFG.PART: | 39393-5 |
| UNSPSC: | 12352100 |
| Manufacturer: | Cayman |
Product Description
Tivantinib is an inhibitor of c-Met (Ki = 0.355 µM). It is selective for c-Met over a panel of 229 additional kinases at 10 µM. Tivantinib also inhibits tubulin polymerization in a cell-free assay in a concentration-dependent manner. It is cytotoxic to c-Met-dependent and -independent cancer cell lines when used at concentrations ranging from 0.01 to 1 µM. Tivantinib (200 mg/kg) reduces tumor growth in HT-29, MKN45, and MDA-MB-231 mouse xenograft models.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3R,4R)-3-(5,6-
CAS Number
905854-02-6
Synonyms
- ARQ 197
Molecular Formula
C23H19N3O2
Formula Weight
369.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/ml
- DMSO: 20 mg/ml
- DMSO:PBS (pH 7.2)(1:5): 0.1 mg/ml
- Ethanol: 5 mg/ml
λmax
224, 281, 289 nm
SMILES
O=C(N1)[C@@H](C2=CNC3=C2C=CC=C3)[C@H](C4=CN5C6=C4C=CC=C6CCC5)C1=O
InChi Code
InChI=1S/C23H19N3O2/c27-22-19(16-11-24-18-9-2-1-7-14(16)18)20(23(28)25-22)17-12-26-10-4-6-13-5-3-8-15(17)21(13)26/h1-3,5,7-9,11-12,19-20,24H,4,6,10H2,(H,25,27,28)/t19-,20-/m0/s1
InChi Key
UCEQXRCJXIVODC-PMACEKPBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-39393-5 |
|---|---|
| Supplier Part Number | 39393-5 |
| UM | EA |
| UNSPSC | 12352100 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/39393m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 37308-75-1 |